Principipal Investigators in the consortium

P04: ROMBY, Pascale & VANDENESCH, F. (Strasbourg, FRANCE)
CNRS, Institut de Biologie Moléculaire et Cellulaire (IBMC), UPR 9002

Dr. Pascale Romby is group leader at the UPR 9002, CNRS. PR obtained her PhD in 1986, spent two postdoc periods at the University of Liège (Belgium) and Vancouver (Canada), and obtained a CNRS researcher position in 1987 in the team led by Prof. Bernard Ehresmann & Dr. Chantal Ehresmann. Her team has, for several years, been involved in the study of structure-function relationships of different RNA molecules involved in translation and posttranscriptional control.

Her group consists of the P.I., one assistant engineer (CNRS), two PhD students, and two postdocs with expertise in RNA structure and RNA-ligand interaction studies. A postdoctoral fellow and a PhD student will be appointed for the project (this application).

Prof. François Vandenesch (Prof., INSERM 0230, Lyon-France) will join P. Romby for this project. F. Vandenesch is responsible of the "French National Reference Center for Staphylococci", and will contribute medical expertise. Beside a significant expertise in the pathogenesis of staphylococcal diseases and toxemia, he has developed genetic tools to study gene expression in S. aureus.

UPR 9002 (Dr. Bernard Ehresmann) is a department located at IBMC (Strasbourg). This institute belongs to the national research organisation CNRS, and houses about 200 researchers working in three departments, covering different fields of molecular and cellular biology. The department consists of around 80 scientists (CNRS, INSERM, ULP) working on different aspects of structure-function of RNA molecules connected with human pathogenesis. The department has all the technical facilities for structural (robot for crystallisation, X-ray analysis, graphic modelling) and molecular biology applications. In addition, the department has direct access to platform technologies (proteomics and mass spectroscopy, protein sequencing, confocal microscopy, protein expression). UPR 9002 is recognized to be one of the leading national centres on RNA in France.

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