KEY REFERENCES

2005

Pillai RS, Bhattacharyya SN, Filipowicz W et al. (2005) "Inhibition of translational initiation by Let-7 MicroRNA in human cells" Science 309(5740):1573-6. PubMed

Filipowicz, W. (2005) RNAi: The nuts and bolts of the RISC machine. Cell 122, 17-20. PubMed

Wassenegger, M. (2005) The role of the RNAi machinery in heterochromatin formation. Cell 122, 13-16. PubMed

Filipowicz W, Jaskiewicz L, Kolb FA, Pillai RS (2005) "Post-transcriptional gene silencing by siRNAs and miRNAs" Curr Opin Struct Biol. 15(3):331-41. PubMed

2004

Bartel DP (2004) MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116(2):281-97 PubMed

Liu J, Carmell MA, Rivas FV, Hannon GJ et al. (2004) Argonaute2 is the catalytic engine of mammalian RNAi. Science 305(5689):1437-41 PubMed

Chen CZ, Li L, Lodish HF, Bartel DP (2004) MicroRNAs modulate hematopoietic lineage differentiation. Science 303(5654):83-6 PubMed

2003

Lee, Y., Ahn, C., Han, J., Choi, H., Kim, J., Yim, J., Lee, J., Provost, P., Radmark, O., Kim, S. and Kim, N. (2003) The nuclear RNaseIII Drosha intitiates microRNA processing. Nature, 425, 415-419. PubMed

Caudy, A.A. et al. (2003) A micrococcal nuclease homologue in RNAi effector complexes. Nature, 425:411-414. PubMed

McManus, M. (2003) MicroRNAs and cancer. Seminars in Cancer Biology, 13, 253-258. PubMed

Johansson, J. and Cossart, P. (2003) RNA-mediated control of virulence gene expression in bacterial pathogens. Trends in Microbiology, 11, 260-284. PubMed

2002

Johansson J, Mandin P, Cossart P et al. (2002) An RNA thermosensor controls expression of virulence genes in Listeria monocytogenes. Cell 110(5):551-61. PubMed

Jenuwein, T. (2002) An RNA-guided pathway for the epigenome. Science, 297, 2215-8. PubMed

Grosshans, H. and Slack, F.J. (2002) Micro-RNAs: small is plentiful. J Cell Biol, 156, 17-21. PubMed

Couzin, J. (2002) Breakthrough of the year. Small RNAs make big splash. Science, 298, 2296-7. PubMed

Llave, C., Xie, Z., Kasschau, K.D. and Carrington J.C.. (2002) Cleavage of Scarecrow-like mRNA targets directed by a class of Arabidopsis miRNA. Science 297, 2053-2056. PubMed

Calin, G.A., Dumitru, C.D., Shimizu, M. et al. (2002) Frequent deletions and down-regulation of micro-RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia. Proc Natl Acad Sci U S A, 99, 15524-29. PubMed

Carmell. M.A. et al. (2002) The Argonaute family: tentacles that reach into RNAi, developmental control, stem cell maintenance, and tumorigenesis. Genes Dev. 16, 2733-2742. PubMed

Zhang, H., Kolb, F.A., Brondani, V., Billy, E. and Filipowicz, W. (2002) Human Dicer preferentially cleaves dsRNAs at their termini without a requirement for ATP. EMBO J. 21, 5875-5885. PubMed

Kiss, T. (2002) Small nucleolar RNAs: an abundant group of noncoding RNAs with diverse cellular functions. Cell, 109, 145-148. PubMed

2001

Argaman, L., Hershberg, R., Vogel, J., Bejerano, G., Wagner, E.G.H., Margalit, H. and Altuvia, S. (2001) Novel small RNA-encoding genes in the intergenic regions of Escherichia coli. Curr Biol, 11, 941-50. PubMed

Elbashir, S.M., Harborth, J., Lendeckel, W., Yalcin, A., Weber, K. and Tuschl, T. (2001) Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature, 411, 494-498. PubMed

2000

Cavaille J et al. (2000) Identification of brain-specific and imprinted small nucleolar RNA genes exhibiting an unusual genomic organisation. Proc Natl Acad Sci U S A. 97:14311-6 PubMed